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frame  International Workshop 2010 - Rauischholzhausen frame
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frame frame Marburg, 21. Sep. 2017 frame
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frame Announcement
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frame Program
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frame Location
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frame Accommodation
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frame Application
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frame Contact
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frame Technical Details
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frame Sponsors
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frame Archive
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frame AG Klebe



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Announcement



Now online:

slides of lectures

abstracts

for receiving the photos contact Ms. Hartleben







Topics and Goals:

A disease pattern is a complex interplay of multiple factors that finally results in a disorder of the entire organism. Correcting the function of one particular target protein is usually the way to interfere with such a disease situation and to subsequently cure by drug therapy. However, we are facing a more complex picture. Interference with highly regulated and multiply interlinked cellular networks occurs even when mainly addressing one single protein. Systems biology tries to approach biology from an integrative rather than a reductionist's point of view. As a consequence, what can systems biology contribute to our field of drug research? Can we expect important insights into the mode of action of drugs, particularly with respect to polypharmacology? Nevertheless, in the planned workshop we do not want to lose sight of molecular aspects of our field of interest. Starting from atomic details of interactions, as captured by quantum chemistry, we want to proceed to computational tools that support the design and ranking of our design hypotheses. The meeting will also cover latest developments in some special and well-established target classes such as kinases or P450 enzymes. What can chemical biology contribute to screening, target discovery and lead discovery? Such techniques help to elucidate details in characterizing protein networks in cells. How much can computational tools support the identification of proteins that mutually talk to each other in signalling cascades? The workshop is intended to address these and similar questions by expert presentations and by fostering discussions among the attendees.

The workshop is organized by:


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