Affinity information for DPC_PDB1A4Q
Chemical Name:
Dihydropyan-Phenethylpropyl-Carboxa
Mide
Molecular Weight: 388.44
Affinity value IC50: 8.5 µM
Experimental Conditions
Method n.a.
Temperature n.a.
pH n.a.
Buffer n.a.
Reagents/Additives n.a.
Literature
Author Smith P. W. et al.
Journal/Source J. Med. Chem., 41, (1998), 787
Literature primary yes
Comment
The IC50 value is the mean of a triplicate measurement and refers to the specific subtype B/Beijing/1/87, which is the subtype in the crystal structure (Ref. J. Med. Chem. 41, 1998, 798 seems to report an average of all B subtypes, instead). - The assay is described in Woods J. M. et al., Antimicrob. Agents Chemother. 37, 1993, 1473 (= ref. 8 of the paper cited above).